Article
Reticulocalbin 3 Deficiency in Alveolar Epithelium Exacerbated Bleomycin-induced Pulmonary Fibrosis.
American journal of respiratory cell and molecular biology - 1 Sept 2018
Jin Jiawei, Shi Xiaoqian, Li Yongchao, Zhang Qianyu, Guo Yu, Li Chaokun, Tan Pingping, Fang Qiuhong, Ma Yingmin, Ma Runlin Z
Abstract excerpt
Reticulocalbin 3 (Rcn3) is an endoplasmic reticulum (ER) lumen protein localized to the secretory pathway. We have reported that Rcn3 plays a critical role in alveolar epithelial type II cell maturation during perinatal lung development, but its biological role in the adult lung is largely unknown. In this study, we found marked induction of Rcn3 expression in alveolar epithelium during bleomycin-induced...
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