Article

T606-phosphorylation deprives the function of Kaiso as a transcription and oncogenic factor

2020-03-25

Abstract excerpt

<h4>ABSTRACT</h4> It is well known that Kaiso protein encoded by ZBTB33 gene is a transcription repressor and that Kaiso–P120ctn interaction increases the shift of Kaiso from the nucleus into the cytoplasm. However, the regulatory mechanisms of Kaiso compartmentalization are far from clear. Here, we reported that AKT1 could phosphorylate 606-threonine residue ( T 606) within the RSS T IP motif of Kaiso in the...

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Literature Corpus work: 81b1bfb4-9dc7-552c-8442-97942b464f0b
DOI: 10.1101/2020.03.23.003509

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