Back to search

Article

Single-Cell and Bulk RNA Sequencing Analysis Reveals CENPA as a Potential Biomarker and Therapeutic Target in Cancers

2024-11-21

Abstract excerpt

<h4>Background: </h4> Cancer is one of the most concerning public health issues in the world. One of cancer hallmarks wildly accepted is sustaining proliferative signaling, which involved most of the cell cycle biological activities. Centromeric histone, Centromere Protein A (CENPA), a variant of canonical histone H3, plays an essential role in selective chromosome segregation in the cell cycle. However, so far, a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
c11c5702-8f74-5d7b-9209-c7c3bc3c15cd
DOI
10.20944/preprints202303.0082.v2
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Single-Cell and Bulk RNA Sequencing Analysis Reveals CENPA as a Potential Biomarker and Therapeutic Target in CancersDOI 10.20944/preprints202303.0082.v2
Single-cell and bulk RNA sequencing analysis reveals CENPA as a potential biomarker and therapeutic target in cancersSemantic proximity
Elevated expression of the centromere protein-A(CENP-A)-encoding gene as a prognostic and predictive biomarker in human cancers.Semantic proximity
Significance of centromere protein genes and their associated immune and metabolic differences in the prediction of prognosis and treatment outcome in breast cancerSemantic proximity
CENPN Acts as a Novel Biomarker that Correlates With the Malignant Phenotypes of Glioma CellsSemantic proximity
Pan-Cancer Analysis Reveals CENPI as a Potential Biomarker and Therapeutic Target in Adrenocortical CarcinomaSemantic proximity
Non-centromeric CENP-A epigenetically regulates epithelial-mesenchymal plasticity and heterogeneity in human cellsSemantic proximity
Prognostic and immune infiltrative biomarkers of CENPO in pan- cancer and its relationship with lung adenocarcinoma cell proliferation and metastasisSemantic proximity
Pan-cancer landscape of CENPO and its underlying mechanism in LUADSemantic proximity
CENPF/CDK1 Signaling Pathway Enhances the Progression of Adrenocortical Carcinoma by Regulating the G2/M-phase Cell CycleSemantic proximity
CENPE is a potentially key molecular biomarker and potential therapeutic target for lung adenocarcinomaSemantic proximity
CENPA facilitates hepatocellular carcinoma proliferation by cooperating with YY1 to drive transcription of CCND1 and NRP2.Semantic proximity
CDCA8, a mitosis-related gene, as a prospective pan-cancer biomarker: implications for survival prognosis and oncogenic immunologySemantic proximity
Select a neighboring publication to make it the new centre.