Article

Linking collective migration/growth to differentiation boosts global shaping of the transcriptome and exhibits a grasshopper effect for driving maturation

2022-07-24

Abstract excerpt

<h4>ABSTRACT</h4> The shift from collective migration to differentiation is a crucial process in epithelial biology but recreating this intricate transition has thus far proved elusive. We provide experimental, mechanistic, in vivo , and bioinformatic data supporting an undoubtable link between human pluripotent stem cell (hPSC)- derived collectively migrating hepatoblasts (MHB), and transcriptionally mature, fu...

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Literature Corpus work: 81aa6695-3604-5cdd-96ee-d3fd1bd4e386
DOI: 10.1101/2022.07.24.501313

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