Article

A high-fidelity in vitro model of the human intestinal epithelium

2024-01-02

Abstract excerpt

Primary intestinal epithelial stem cell culture methods have significantly advanced understanding of mammalian intestinal development and disease. However, progress has been hampered by inconsistent methodological reporting and challenges comparing in vitro systems with in vivo observations. We previously established a unique method for long-term 2dimensional (2D) cultivation of mouse lECs using an air-liquid i...

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Literature Corpus work: 0fb92fcf-43a9-59c5-8006-b9fac852c42e
DOI: 10.1101/2024.01.01.573838

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