Article

Serotonin signaling in the enteric nervous system and connection to autism spectrum disorder: a translational mathematical model

2022-10-14

Abstract excerpt

While the causes of autism spectrum disorder (ASD) remain unclear, some studies have shown that serotonin-mediated effects on enteric nervous system (ENT) correlate with ASD-like behavioral phenotype in mice. Introduced here is a mathematical model of interactions between gut serotonin and its impact on ENT. The model was used to identify three key factors that affect ENT size, namely, serotonin production, its cl...

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Literature Corpus work: 814d5803-f611-5ded-9335-1e0d6526fcf6
DOI: 10.1101/2022.10.11.511819

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