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Detection of serotonin and serotonin related gene reveals unique roles in human intestinal epithelial development

2025-12-01

Abstract excerpt

Although 95% of serotonin in the human body is produced in the gastrointestinal tract, most prior research work has focused on the brain. Despite its abundance in the gut, serotonin’s role in early intestinal development remains poorly understood. Here we show that serotonin is detected in both the small intestine and large intestine as early as 14-15 weeks gestational age. Using single-cell transcriptomics with h...

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Identifiers and source

Literature Corpus work
5505a81c-2ad2-5c6e-bd12-1dc2b8ffae40
DOI
10.1101/2025.11.27.690965
Open publication

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Detection of serotonin and serotonin related gene reveals unique roles in human intestinal epithelial developmentDOI 10.1101/2025.11.27.690965
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