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Article

The serotonin-N-acetylserotonin–melatonin pathway as a biomarker for autism spectrum disorders

11 Nov 2014

Abstract excerpt

Elevated whole-blood serotonin and decreased plasma melatonin (a circadian synchronizer hormone that derives from serotonin) have been reported independently in patients with autism spectrum disorders (ASDs). Here, we explored, in parallel, serotonin, melatonin and the intermediate N-acetylserotonin (NAS) in a large cohort of patients with ASD and their relatives. We then investigated the clinical correlates of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25386956
DOI: 10.1038/tp.2014.120

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