Article

GWAS on short tandem repeats identifies novel genetic mechanisms in Alzheimer’s disease

2025-03-13

Abstract excerpt

Genome-wide association studies (GWASs) are typically based on the analysis of single nucleotide polymorphisms (SNPs) and often exclude more complex genetic variants, such as short tandem repeats (STRs). Here, we report the results of GWAS analyses systematically assessing the role of STRs, both imputed and directly genotyped by whole genome sequencing (WGS), on risk for Alzheimer’s disease (AD) in a large collect...

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Literature Corpus work: 81287bec-e1b7-5e03-aafe-cf64cc5b26fc
DOI: 10.1101/2025.03.13.25323833

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