Article
SARS-CoV-2 spike protein induces TLR-4-mediated long-term cognitive dysfunction recapitulating post-COVID syndrome
2022-06-08
Abstract excerpt
Cognitive dysfunction is often reported in post-COVID patients, but its underlying mechanisms remain unknown. While some evidence indicate that SARS-CoV-2 can reach and directly impact the brain, others suggest viral neuroinvasion as a rare event. Independently of brain viral infection, the ability of SARS-CoV-2 spike (S) protein to cross the BBB and reach memory-related brain regions has already been shown. Here,...
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Identifiers and source
- Literature Corpus work
- 810a2f5d-282b-5d85-8d8c-47c43f861025
- DOI
- 10.1101/2022.06.07.495149