Article

Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors

2020-04-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Rett syndrome (RTT) is a progressive neurodevelopmental disease that is characterized by abnormalities in cognitive, social and motor skills. RTT is often caused by mutations in the X-linked gene encoding methyl-CpG binding protein 2 (MeCP2). The mechanism by which impaired MeCP2 induces the pathological abnormalities in the brain is not understood. Both patients...

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Literature Corpus work: 29341bb3-dd15-5e66-b8eb-a5f301ca5367
DOI: 10.21203/rs.3.rs-15527/v2

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