Article

A feline model of human LDLR-related atherosclerosis

2024-12-07

Abstract excerpt

<h4>Background: </h4> Atherosclerosis, a chronic inflammatory vascular disease driven by the accumulation of LDL-derived cholesterol on arterial walls, is the leading cause of mortality worldwide but is rare in animals. We recently identified spontaneous atherosclerosis in the Korat cat breed, characterized by severe hypercholesterolemia and clinical signs of congestive heart failure, ultimately leading to death....

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Literature Corpus work: 80f1a9bd-d139-5c4e-9c68-ab61ccfaa2f1
DOI: 10.1101/2024.12.04.626782

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