Genetics of feline hypertrophic cardiomyopathy.

doi:10.1111/cge.13743

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Article

Genetics of feline hypertrophic cardiomyopathy.

Clinical genetics - 1 Sept 2020

Gil-Ortuño Cristina, Sebastián-Marcos Patricia, Sabater-Molina María, Nicolas-Rocamora Elisa, Gimeno-Blanes Juan R, Fernández Del Palacio María J

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is characterized by an abnormal increase in myocardial mass that affects cardiac structure and function. HCM is the most common inherited cardiovascular disease in humans (0.2%) and the most common cardiovascular disease in cats (14.7%). Feline HCM phenotype is very similar to the phenotype found in humans, but the time frame for the development of the disease is significantly...

Topics

Animals
Cardiac Myosins
Cardiomyopathy, Hypertrophic
Carrier Proteins
Cat Diseases
Cats
Disease Models, Animal
Genetic Predisposition to Disease
Humans
Myosin Heavy Chains
Sarcomeres

Source

Open in PubMed

Identifiers

PMID: 32215921
DOI: 10.1111/cge.13743

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