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Article

Unraveling the genetics of feline hypertrophic cardiomyopathy: a multiomics study of 138 cats.

G3 (Bethesda, Md.) - 3 Sept 2025

Kaplan Joanna L, Rivas Victor N, Vandewege Michael W, Wouters Jalena R, Harris Samantha P, Meurs Katherine M, Stern Joshua A

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease in cats, often leading to congestive heart failure, arterial thromboembolism, and sudden cardiac death. The genetics of feline HCM are poorly understood and limited genetic discoveries remain breed- or family-specific. We aimed to identify novel causative or disease-modifying variants in a large cohort of cats reflective of the general...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40609041
DOI: 10.1093/g3journal/jkaf153
PMCID: PMC12405878

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