Article

Exercise training improves exercise capacity independent of AMPKα2 T172-mediated adaptations in skeletal muscle

2026-06-23

Abstract excerpt

Regular exercise induces adaptations in skeletal muscle and other organ systems to improve physical performance and overall health. Exercise results in phosphorylation of 5’ AMP-activated protein kinase (AMPK) at threonine 172 (T172) of the α2 subunit; however, the role of this activation in cellular and functional adaptations has not been elucidated. To this end, we subjected non-activatable Ampkα2 ( T172A ) kn...

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Literature Corpus work: 80bb9e5f-5bfe-5fef-b1cd-78c5c5c4aefa
DOI: 10.64898/2026.06.18.733224

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