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A comprehensive preimplantation genetic testing approach for SEA-type α-thalassemia by fluorescent Gap-polymerase chain reaction combined with haplotype analysis

2023-04-21

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold> This study aims to evaluate the feasibility and necessity of using fluorescence Gap-polymerase chain reaction (PCR) combined with haplotype analysis in preimplantation genetic testing (PGT) for SEA-type α-thalassemia.<bold>Methods</bold> Twenty-six PGT biopsy cycles were performed in 25 families from June 2021 to February 2022. All couples were carriers of the SEA-t...

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Literature Corpus work: 80a21e4a-f059-54a3-a3e4-aa57e91a2b02
DOI: 10.21203/rs.3.rs-2825846/v1

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