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Article

Preimplantation genetic diagnosis of alpha-thalassemia-SEA using novel multiplex fluorescent PCR.

Journal of assisted reproduction and genetics - 1 Jan 2012

Piyamongkol Wirawit, Vutyavanich Teraporn, Sanguansermsri Torpong

Abstract excerpt

PURPOSE: Preimplantation genetic diagnosis (PGD) is an alternative to prenatal diagnosis (PND) giving couples at risk a chance to start a pregnancy with a disease-free baby. This study aimed to develop a new PGD protocol for alpha-thalassemia(-SEA) mutation, the commonest Mendelian disorder. PATIENTS AND METHODS: Multiplex fluorescent PCR was employed for mutation, contamination and linkage analysis. A couple...

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Source

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Identifiers

PMID: 21964516
DOI: 10.1007/s10815-011-9641-6
PMCID: PMC3252417

Genes

SEA
PGD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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