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Spontaneous object exploration in a recessive gene knockout model of Parkinson’s disease: Development and progression of object recognition memory deficits in male <i>Pink1</i> -/- rats

2022-05-24

Abstract excerpt

<h4>ABSTRACT</h4> Cognitive impairments appear at or before motor signs in about one third of patients with Parkinson’s disease (PD) and have a cumulative prevalence of roughly 80% overall. These deficits exact an unrelenting toll on patients’ quality and activities of daily life due in part to a lack of available treatments to ameliorate them. This study used three well-validated novel object recognition-based p...

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Literature Corpus work: 80940ab3-1546-5687-8f12-666257958cea
DOI: 10.1101/2022.05.23.493123

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