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Dissociable cognitive impairments in two strains of transgenic Alzheimer’s disease mice revealed by a battery of object-based tests

7 Jan 2019

Abstract excerpt

Object recognition tasks detect cognitive deficits in transgenic Alzheimer's disease (AD) mouse models. Object recognition, however, is not a unitary process, and there are many uncharacterized facets of object processing with relevance to AD. We therefore systematically evaluated object processing in 5xFAD and 3xTG AD mice to clarify the nature of object recognition-related deficits. Twelve-month-old male and...

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Alzheimer's disease research and treatments
Memory and Neural Mechanisms
Neuroscience and Neuropharmacology Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30635592
DOI: 10.1038/s41598-018-37312-0

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