Article

Signals of Human Polygenic Adaptation: Moving Beyond Single-Gene Methods and Controlling for Population-Specific Linkage Disequilibrium

2023-07-18

Abstract excerpt

This research aimed to identify signals of polygenic adaptation in various phenotypes – such as educational attainment, height, and schizophrenia – by employing traditional Fst enrichment tests and polygenic score differentiation tests like Qst and Qx. Fst tests offered inconclusive evidence for over-differentiation in allele frequencies, while Qst tests indicated significant differences for cognitive traits but n...

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Literature Corpus work: 80917022-fc52-50f7-bf20-fc326b048de0
DOI: 10.32388/hdjk5p

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