Article

EPB41L4A-AS1 modulates Aβ clearance by regulating autophagy-related gene expression

2023-11-01

Abstract excerpt

<title>Abstract</title> <p>Alzheimer's disease (AD) is the most common neurodegenerative disorder characterized by the deposition of β-amyloid (Aβ) plaques. Aβ is generated from the cleavage of the amyloid precursor protein by β and γ-secretases and cleared by neuroglial cells mediated autophagy. The imbalance of the intracellular Aβ generation and clearance is the causative factor for AD pathogenesis. However, t...

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Literature Corpus work: 806cd067-0492-5f7f-8126-8d05e511f78c
DOI: 10.21203/rs.3.rs-3429473/v1

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