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Plasma long non-coding RNA BACE1 as a novel biomarker for diagnosis of Alzheimer disease

9 Jan 2018

Abstract excerpt

BACKGROUNDS: Long non-coding RNA (LncRNA) have been reported to be involved in the pathogenesis of neurodegenerative diseases, but whether it can serve as a biomarker for Alzheimer disease (AD) is not yet known. METHODS: The present study selected four specific LncRNA (17A, 51A, BACE1 and BC200) as possible AD biomarker. RT-qPCR was performed to validate the LncRNA. Receiver operating characteristic curve (ROC)...

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PMID: 29316899
DOI: 10.1186/s12883-017-1008-x

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