Article
Deciphering lysosomal autophagy-linked differential gene signatures in Alzheimer’s disease: Multicohort bioinformatics analysis leveraging Gene Expression Omnibus datasets
2026-06-30
Abstract excerpt
<title>Abstract</title> <p> Background Contemporary clinical frameworks for Alzheimer’s disease (AD) rely predominantly on symptomatic surveillance, rehabilitative interventions, and supportive care. This investigation aimed to delineate lysosomal autophagy-associated differentially expressed genes (LARDEGs) within AD. Methods Using publicly accessible repositories, differentially expressed transcripts were id...
Topics
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- Alzheimer's disease research and treatments
- Autophagy in Disease and Therapy
- Bioinformatics and Genomic Networks
- Dementia and Cognitive Impairment Research
- Lysosomal Storage Disorders Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Parkinson's Disease Mechanisms and Treatments
- Tryptophan and brain disorders
Identifiers and source
- Literature Corpus work
- c07d9963-d037-509d-9509-9f7ed91cf14c
- DOI
- 10.21203/rs.3.rs-9778769/v1
