Article

Activin-A Impedes the Establishment of CD4+ T Cell Exhaustion and Enhances Anti-Tumor Immunity in the Lung

2021-07-13

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Although tumor-infiltrating T cells represent a favorable prognostic marker for cancer patients, the majority of these cells are rendered with an exhausted phenotype. Hence, there is an unmet need to identify factors which can reverse this dysfunctional profile and restore their anti-tumorigenic potential. Activin-A is a pleiotropic cytokine, exerting a broad ra...

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Literature Corpus work: 805a8c5d-4354-5c2f-a457-a0f57d5f5f38
DOI: 10.21203/rs.3.rs-695724/v1

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