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Article

Paracrine Activin-A Signaling Promotes Melanoma Growth and Metastasis through Immune Evasion.

The Journal of investigative dermatology - 1 Dec 2017

Donovan Prudence, Dubey Olivier A, Kallioinen Susanna, Rogers Katherine W, Muehlethaler Katja, Müller Patrick, Rimoldi Donata, Constam Daniel B

Abstract excerpt

The secreted growth factor Activin-A of the transforming growth factor β family and its receptors can promote or inhibit several cancer hallmarks including tumor cell proliferation and differentiation, vascularization, lymphangiogenesis and inflammation. However, a role in immune evasion and its relationship with tumor-induced muscle wasting and tumor vascularization, and the relative contributions of autocrine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28844941
DOI: 10.1016/j.jid.2017.07.845

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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