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Extrachromosomal MicroDNA as a Novel Layer of Post-Transcriptional Regulation of the Deiodinase Axis in Autoimmune Thyroiditis: An In Silico Interaction Network Analysis

2026-06-16

Abstract excerpt

<title>Abstract</title> <p>Objective To investigate whether human microDNA loci harbor sequence motifs with sufficient thermodynamic stability to interact with deiodinase-regulatory miRNAs and to evaluate their theoretical relevance in autoimmune thyroiditis. Methods A fully in silico workflow was developed using publicly available genomic resources. Human microDNA loci were modeled from published Circle-Seq da...

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Literature Corpus work
804876d5-8e20-5071-b09d-84e095510896
DOI
10.21203/rs.3.rs-10029715/v1
Open publication

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Extrachromosomal MicroDNA as a Novel Layer of Post-Transcriptional Regulation of the Deiodinase Axis in Autoimmune Thyroiditis: An In Silico Interaction Network AnalysisDOI 10.21203/rs.3.rs-10029715/v1
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