Article

A stress-function tradeoff organizes epithelial heterogeneity across spatial scales in the human thyroid

2026-03-16

Abstract excerpt

Many organs are organized into repeating anatomical units, yet how cellular heterogeneity is structured within and between these units remains poorly understood. Here we use spatial transcriptomics to dissect multiscale heterogeneity in the human thyroid gland, a tissue composed of hormone-producing follicles. Across human thyroid samples spanning non-inflamed to inflamed states, we develop a follicle-aware analyt...

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Identifiers and source

Literature Corpus work: 20304f2c-11f9-53ab-b992-202a4ff0a280
DOI: 10.64898/2026.03.12.711294

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