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Article

Association of miR-499 Polymorphism and Its Regulatory Networks with Hashimoto Thyroiditis Susceptibility: A Population-Based Case-Control Study.

International journal of molecular sciences - 18 Sept 2021

Tabasi Farhad, Hasanpour Vahed, Sarhadi Shamim, Kaykhaei Mahmoud Ali, Pourzand Pouria, Heravi Mehrdad, Langari Ahmad Alinaghi, Bahari Gholamreza, Taheri Mohsen, Hashemi Mohammad, Ghavami Saeid

Abstract excerpt

Hashimoto thyroiditis (HT) is a common autoimmune disorder with a strong genetic background. Several genetic factors have been suggested, yet numerous genetic contributors remain to be fully understood in HT pathogenesis. MicroRNAs (miRs) are gene expression regulators critically involved in biological processes, of which polymorphisms can alter their function, leading to pathologic conditions, including...

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Identifiers

PMID: 34576267
DOI: 10.3390/ijms221810094
PMCID: PMC8470033

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