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Article

Proteomics analysis of cellular components in lentiviral vector production using Gel-LC-MS/MS.

2007-02-01

Abstract excerpt

Among the gene therapy vectors developed to date, lentiviral vectors persist in the host and are therefore best suited for long-term gene transfer and gene-replacement therapies. Human immunodeficiency virus (HIV)-1-based lentiviral vector products are currently produced by transient transfection, filtration and ultracentrifugation, and the quality of the resultant vector product is variable. We reason that by ide...

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Identifiers and source

Literature Corpus work
8040367a-45b9-5ab8-a1d4-2245a0eb64e3
DOI
10.1002/prca.200600522
Open publication

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Proteomics analysis of cellular components in lentiviral vector production using Gel-LC-MS/MS.DOI 10.1002/prca.200600522
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