Article

Characterization of Extracellular Vesicles Secreted in Lentiviral Producing HEK293SF Cell Cultures

2021-03-29

Abstract excerpt

Lentiviral vectors (LVs) are a powerful tool for gene and cell therapy and human embryonic kidney cells (HEK293) have been extensively used as a platform for production of these vectors. Like most cells and cellular tissues, HEK293 cells release extracellular vesicles (EVs). EVs released by cells share similar size, biophysical characteristics and even a biogenesis pathway with cell-produced enveloped viruses, mak...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cf796e58-c7c4-5867-9d8b-c465eed99048
DOI: 10.20944/preprints202103.0696.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Characterization of Extracellular Vesicles Secreted in Lentiviral Producing HEK293SF Cell CulturesDOI 10.20944/preprints202103.0696.v1Read

Before Translating Extracellular Vesicles into Personalized Diagnostics and Therapeutics: What We Could DoSemantic proximity Read

Experimental and Biological Insights from Proteomic Analyses of Extracellular Vesicle Cargos in Normalcy and DiseaseSemantic proximity Read

Cloaked Viruses and Viral Factors in Cutting Edge Exosome-Based TherapiesSemantic proximity Read

Extracellular Vesicles in Viral Replication and Pathogenesis and Their Potential Role in Therapeutic InterventionSemantic proximity Read

Small-scale bioreactor cultivation of HEK293-based suspension cells increases extracellular vesicle yieldSemantic proximity Read

Humanized Extracellular Vesicles for Efficient RNA DeliverySemantic proximity Read

Extracellular Vesicles as Mediators of Intercellular Communication: Implications for Drug Discovery and Targeted TherapiesSemantic proximity Read

Techniques used for the isolation and characterization of extracellular vesicles: results of a worldwide surveySemantic proximity Read

Production of lentiviral vectorsSemantic proximity Read

Emerging technologies in extracellular vesicle-based molecular diagnosticsSemantic proximity Read

Serum extracellular vesicle depletion processes affect release and infectivity of HIV-1 in cultureSemantic proximity Read

Filter-aided extracellular vesicle enrichment (FAEVEr) for proteomicsSemantic proximity Read