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Article

Analysis of purified wild type and mutant adenovirus particles by SILAC based quantitative proteomics.

The Journal of general virology - 1 Nov 2014

Alqahtani Ali, Heesom Kate, Bramson Jonathan L, Curiel David, Ugai Hideyo, Matthews David A

Abstract excerpt

We used SILAC (stable isotope labelling of amino acids in cell culture) and high-throughput quantitative MS mass spectrometry to analyse the protein composition of highly purified WT wild type adenoviruses, mutant adenoviruses lacking an internal protein component (protein V) and recombinant adenoviruses of the type commonly used in gene therapy, including one virus that had been used in a clinical trial. We...

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Identifiers

PMID: 25096814
DOI: 10.1099/vir.0.068221-0
PMCID: PMC4202269

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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