Article

Nanoparticle endocytosis is driven by monocyte phenotype rather than nanoparticle size under high shear flow conditions

2023-06-29

Abstract excerpt

Monocytes are members of the mononuclear phagocyte system involved in pathogen clearance and nanoparticle pharmacokinetics. Monocytes play a critical role in the development and progression of cardiovascular disease and, recently, in SARS-CoV-2 pathogenesis. While studies have investigated the effect of nanoparticle modulation on monocyte uptake, their capacity for nanoparticle clearance is poorly studied. In this...

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Literature Corpus work: 800e2eef-08d6-5830-848c-acac0523bdda
DOI: 10.1101/2023.06.29.547038

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