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Article

On-chip endothelial inflammatory phenotyping.

Journal of visualized experiments : JoVE - 21 Jul 2012

DeVerse J Sherrod, Bailey Keith A, Foster Greg A, Mittal Vaishali, Altman Stuart M, Simon Scott I, Passerini Anthony G

Abstract excerpt

Atherogenesis is potentiated by metabolic abnormalities that contribute to a heightened state of systemic inflammation resulting in endothelial dysfunction. However, early functional changes in endothelium that signify an individual's level of risk are not directly assessed clinically to help guide therapeutic strategy. Moreover, the regulation of inflammation by local hemodynamics contributes to the non-random...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22847646
DOI: 10.3791/4169
PMCID: PMC3476418

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TNF

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