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Article

Distinct malignant cell states and myeloid glutamate signaling associated with aggressive pancreatic neuroendocrine tumors

2025-07-19

Abstract excerpt

Pancreatic neuroendocrine tumors (PNET) are rare malignancies of the endocrine pancreas with diverse clinical outcomes. While some PNETs are indolent, others are aggressive and metastasize quickly. However, clinically-relevant molecular stratification for PNET to predict outcomes and guide therapeutic decision-making is limited. Thus, there is an urgent need to understand the molecular heterogeneity of PNETs to re...

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Literature Corpus work
7ff28529-0201-561d-844a-4160ced95df7
DOI
10.1101/2025.07.15.664730
Open publication

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Distinct malignant cell states and myeloid glutamate signaling associated with aggressive pancreatic neuroendocrine tumorsDOI 10.1101/2025.07.15.664730
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