Article

Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors

2022-11-09

Abstract excerpt

<h4>ABSTRACT</h4> Neuroendocrine tumors (NETs) are rare cancers that may arise in the gastrointestinal tract and pancreas. The fundamental mechanisms driving gastroenteropancreatic (GEP) NET growth remain incompletely elucidated; however, the heterogeneous clinical behavior of GEP-NETs suggests that both cellular lineage dynamics and tumor microenvironment influence tumor pathophysiology. Here, we investigated th...

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Literature Corpus work: 365224a8-1e13-570b-b497-ca18127993d0
DOI: 10.1101/2022.11.08.515538

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