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Multiomic Spatial Imaging Assay (MSIA) – A High-plex <i>In Situ</i> Detection Method for mRNAs, Proteins and Protein-Protein Interactions using Manual And Semi-Automated Workflows

2026-03-02

Abstract excerpt

We report Multiomics Spatial Image Analysis (MSIA), a suite of technologies that include streamlined manual and semi-automated workflows to image 100s of RNAs from fresh frozen and formalin-fixed paraffin-embedded (FFPE) samples, contextualize RNAs with select protein markers including imaging synaptic protein interactions, a data analysis pipeline that includes corrections for chromatic aberration, algorithms for...

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Literature Corpus work
7fd6d20e-f4b4-5104-aa11-fa91bc51606e
DOI
10.64898/2026.02.26.708124
Open publication

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Multiomic Spatial Imaging Assay (MSIA) – A High-plex <i>In Situ</i> Detection Method for mRNAs, Proteins and Protein-Protein Interactions using Manual And Semi-Automated WorkflowsDOI 10.64898/2026.02.26.708124
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