Article

GPU-accelerated, self-optimizing processing for 3D multiplexed iterative RNA-FISH experiments

2025-10-13

Abstract excerpt

<h4>SUMMARY</h4> Imaging-based spatial transcriptomic approaches rely on iterative labeling and imaging of carefully prepared samples, followed by solving a computational inverse problem to determine the location and identity of the targeted RNA. Because these approaches require high-resolution optics, the Nyquist-Shannon determined voxel size is small relative to typical tissue sample footprints. A common soluti...

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Literature Corpus work: 5770c6da-9632-59c1-a21c-94b5db73a91b
DOI: 10.1101/2025.10.10.681751

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