Article

OmniCell: Unified Foundation Modelling of Single-Cell and Spatial Transcriptomics for Cellular and Molecular Insights

2025-12-29

Abstract excerpt

A cell’s transcriptional programme is not fully defined by gene expression alone, but by the tissue context in which that programme is enacted. Single-cell RNA sequencing resolves molecular identity after dissociation, whereas spatial transcriptomics preserves tissue architecture but remains constrained by assay-specific sparsity and gene coverage. Here we present OmniCell, a tissue-contextual transcriptomic found...

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Literature Corpus work: befce1a5-3a32-5acd-890d-55deac875399
DOI: 10.64898/2025.12.29.696804

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