Article

Aging gene signature of IL-7 receptor alpha low effector memory CD8+ T cells is associated with neurocognitive functioning in Alzheimer’s disease

2023-04-04

Abstract excerpt

<title>Abstract</title> CD45RA+ effector memory (EM) CD8+ T cell expansion was reported in Alzheimer’s disease (AD). Such cells are IL-7 receptor alpha (IL-7Rα)low EM CD8+ T cells, which expand with age and have a unique aging gene signature (i.e., IL-7Rαlow aging genes). Here we investigated whether IL-7Rαlow aging genes and previously reported...

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Literature Corpus work: 7f79dcb2-aed7-5707-9055-b9cd08910c01
DOI: 10.21203/rs.3.rs-2736771/v1

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