Article

Human pulmonary neuroendocrine cells respond to House dust mite extract with PAR-1 dependent release of CGRP

2024-09-09

Abstract excerpt

<h4>Background: </h4> Pulmonary neuroendocrine cells (PNEC) are rare airway epithelial cells that have recently gained attention as potential amplifiers of allergic asthma. However, studying PNEC function in humans has been challenging due to a lack of cell isolation methods and little is known about human PNEC function in response to asthma relevant stimuli. Here we developed and characterized an in vitro human P...

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Literature Corpus work: 7f6baa72-e505-5dca-aa67-a964e2eaed89
DOI: 10.1101/2024.09.09.612124

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