Article

Human placental extract regulates polarization of macrophages via IRGM/NLRP3 in allergic rhinitis

2022-12-29

Abstract excerpt

<h4>Background: </h4> Allergic rhinitis (AR) is globally prevalent and its pathogenesis remains unclear. Alternative activation of macrophages is suggested in AR and thought to be involved in natural immunoregulatory processes in AR. Aberrant activation of Nod-like receptor protein 3 (NLRP3) inflammasome is linked with AR. Human placenta extract (HPE) is widely used in clinics due to its multiple therapeutic poten...

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Literature Corpus work: b68c44fb-d9b1-588b-871c-27ff5a6dd311
DOI: 10.21203/rs.3.rs-2394154/v1

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