Article

Metabolic regulation by prostaglandin E 2 impairs lung group 2 innate lymphoid cell responses

2021-12-28

Abstract excerpt

<h4>Background: </h4> Group 2 innate lymphoid cells (ILC2s) play a critical role in asthma pathogenesis. Non-steroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (NERD) is associated with reduced signaling via EP2, a receptor for prostaglandin E 2 (PGE 2 ). However, the respective roles for the PGE 2 receptors EP2 and EP4 (both share same downstream signaling) in the regulation of lung ILC2...

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Literature Corpus work: c0e48927-6d6c-5219-bfe1-19026077ec4e
DOI: 10.22541/au.164068294.41852173/v1

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