Article
Chemosensory functions for pulmonary neuroendocrine cells.
American journal of respiratory cell and molecular biology - 1 Mar 2014
Gu Xiaoling, Karp Philip H, Brody Steven L, Pierce Richard A, Welsh Michael J, Holtzman Michael J, Ben-Shahar Yehuda
Abstract excerpt
The mammalian airways are sensitive to inhaled stimuli, and airway diseases are characterized by hypersensitivity to volatile stimuli, such as perfumes, industrial solvents, and others. However, the identity and function of the cells in the airway that can sense volatile chemicals remain uncertain, particularly in humans. Here, we show that solitary pulmonary neuroendocrine cells (PNECs), which are...
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