Article

Challenges of CRISPR-based Gene Editing in Primary T Cells

2022-01-11

Abstract excerpt

Adaptive T cell immunotherapy holds great promise for the successful treatment of leukemia as well as other types of cancers. More recently, it was also shown to be an effective treatment option for chronic virus infections in immunosuppressed patients. Autologous or allogeneic T cells used for immunotherapy are usually genetically modified to express novel T cell or chimeric antigen receptors. The production of s...

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Literature Corpus work: 7f36f3ae-f6fe-5b1f-b0a2-8ddb5d481950
DOI: 10.20944/preprints202201.0137.v1

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