Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CRISPR/Cas9-based genome editing in the era of CAR T cell immunotherapy

8 Feb 2019

Abstract excerpt

The advent of engineered T cells as a form of immunotherapy marks the beginning of a new era in medicine, providing a transformative way to combat complex diseases such as cancer. Following FDA approval of CAR T cells directed against the CD19 protein for the treatment of acute lymphoblastic leukemia and diffuse large B cell lymphoma, CAR T cells are poised to enter mainstream oncology. Despite this success, a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to CRISPR and Genetic Engineering
Share to Viral Infectious Diseases and Gene Expression in Insects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30735463
DOI: 10.1080/21645515.2019.1571893

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CRISPR/Cas9-based genome editing in the era of CAR T cell immunotherapyPMID 30735463Read ↗

Engineering the next-generation of CAR T-cells with CRISPR-Cas9 gene editingSemantic proximity Read ↗

Strengthening the CAR-T Cell Therapeutic Application using CRISPR/Cas9 TechnologySemantic proximity Read ↗

A Comprehensive Review of Recent Advancements in Cancer Immunotherapy and Generation of CAR T Cell by CRISPR-Cas9Semantic proximity Read ↗

CRISPR–Cas9 applications in T cells and adoptive T cell therapiesSemantic proximity Read ↗

Building Potent Chimeric Antigen Receptor T Cells With CRISPR Genome EditingSemantic proximity Read ↗

CRISPR/Cas9 revitalizes adoptive T-cell therapy for cancer immunotherapySemantic proximity Read ↗

Therapeutic potential of CRISPR/Cas9 gene editing in engineered T‐cell therapySemantic proximity Read ↗

Applications and explorations of CRISPR/Cas9 in CAR T-cell therapySemantic proximity Read ↗

Applications of CRISPR Genome Editing to Advance the Next Generation of Adoptive Cell Therapies for CancerSemantic proximity Read ↗

Boosting CAR-T cell therapy with CRISPR technologySemantic proximity Read ↗

Strengthening the CAR‐T cell therapeutic application using CRISPR/Cas9 technologySemantic proximity Read ↗

CRISPR/Cas9-Mediated Customizing Strategies for Adoptive T-Cell TherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.