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CRISPR/Cas9-Mediated Customizing Strategies for Adoptive T-Cell Therapy

1 Mar 2024

Abstract excerpt

Clustered regularly interspaced short palindromic repeat-associated protein Cas9 (CRISPR/Cas9) technology is at the forefront of cancer immunotherapy innovation, offering precise and personalized treatment strategies. In this review, we discuss CRISPR/Cas9's ability to precisely edit the genome, its impact on immune checkpoint control, and its application in immune cell engineering, where it surpasses traditional...

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PMID: 38543240
DOI: 10.3390/pharmaceutics16030346

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