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CRISPR/Cas9 revitalizes adoptive T-cell therapy for cancer immunotherapy

26 Aug 2021

Abstract excerpt

Cancer immunotherapy has gained attention as the supreme therapeutic modality for the treatment of various malignancies. Adoptive T-cell therapy (ACT) is one of the most distinctive modalities of this therapeutic approach, which seeks to harness the potential of combating cancer cells by using autologous or allogenic tumor-specific T-cells. However, a plethora of circumstances must be optimized to produce...

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PMID: 34446084
DOI: 10.1186/s13046-021-02076-5

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