Article
Age-Related Cognitive Changes as a Function of CAG Repeat in Child and Adolescent Carriers of Mutant Huntingtin.
Annals of neurology - 1 May 2021
Schultz Jordan L, van der Plas Ellen, Langbehn Douglas R, Conrad Amy L, Nopoulos Peg C
Abstract excerpt
Limited data exists regarding the disease course of Huntington's Disease (HD) in children and young adults. Here, we evaluate the trajectory of various cognitive skill development as a function of cytosine-adenine-guanine (CAG) repeat length in children and adolescents that carry the mutation that causes HD. We discovered that the development of verbal skills seems to plateau earlier as CAG repeat length...
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