Article

Patient-Specific Pharmacogenomics unveils xCT as a Key Regulator for Druggable Metabolic and Proliferation Pathways in Colon Cancer

2025-02-18

Abstract excerpt

Colorectal cancer (CRC) represents the third-leading cause of cancer-related deaths. Knowledge covering diverse cellular and molecular data from individual patients has become valuable for diagnosis, prognosis, and treatment selection. Here, we present an in-depth comparative mRNA-seq and microRNA-seq analysis of tissue samples from 32 CRC, pairing tumors with adjacent healthy tissues. The differential expression...

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Literature Corpus work: a77531ab-6e33-52ff-b040-db6530f1292a
DOI: 10.1101/2025.02.11.637634

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