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Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions

2022-04-04

Abstract excerpt

Solute carrier (SLC) transporters control fluxes of nutrients and metabolites across membranes and thereby represent a critical interface between the microenvironment and cellular and subcellular metabolism. Because of substantial functional overlap, the interplay and relative contributions of members of this family in response to environmental stresses remain poorly elucidated. In order to infer functional relati...

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Literature Corpus work
9a85525a-12a1-57a1-843a-1847f5b282f3
DOI
10.1101/2022.04.03.486870
Open publication

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Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictionsDOI 10.1101/2022.04.03.486870
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